Group A streptococcal (Streptococcus pyogenes) bacteremia in children
- Dennis L Stevens, MD, PhD
Dennis L Stevens, MD, PhD
- Professor of Medicine
- University of Washington School of Medicine
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
Group A streptococcus (GAS, eg, Streptococcus pyogenes) is an aerobic gram-positive coccus that is a common cause of acute bacterial pharyngitis and other cutaneous and invasive infections in children . Invasive GAS infections are defined as bacteremia, pneumonia, osteomyelitis, septic arthritis, or any other infection associated with the isolation of GAS from a normally sterile body site . Invasive infections also include necrotizing fasciitis and spontaneous gangrenous myositis.
The epidemiology, clinical manifestations, treatment, and prognosis of GAS bacteremia and/or invasive GAS infection in children will be reviewed here. GAS bacteremia in adults and issues related to specific manifestations of invasive GAS infections (toxic shock syndrome and necrotizing fasciitis) are discussed separately:
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