The role of granulocyte transfusions in neutropenic patients

Br J Haematol. 2004 Dec;127(5):501-8. doi: 10.1111/j.1365-2141.2004.05221.x.

Abstract

The precise role for donor granulocyte infusions remains to be delineated, partly because of the lack of defined clinical trials. The aim of this article is to summarize the studies undertaken so far and highlight the logistical problems associated with undertaking future studies. We also aim to provide a practical guide to the application of this therapeutic approach.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacterial Infections / therapy*
  • Granulocyte Colony-Stimulating Factor / therapeutic use
  • Granulocytes*
  • Humans
  • Immunocompromised Host
  • Leukocyte Transfusion*
  • Neutropenia / therapy*

Substances

  • Granulocyte Colony-Stimulating Factor