|A Grade 2B recommendation is a weak
recommendation; alternative approaches may be better for some patients
under some circumstances.
|A Grade 2 recommendation is a weak recommendation.
It means "this is our suggestion, but you may want to think about it."
It is unlikely that you should follow the suggested approach in all
your patients, and you might reasonably choose an alternative approach.
For Grade 2 recommendations, benefits and risks may be finely balanced,
or the benefits and risks may be uncertain. In deciding whether to
follow a Grade 2 recommendation in an individual patient, you may want
to think about your patient's values and preferences or about
your patient's risk aversion.
|Grade B means that the best estimates
of the critical benefits and risks come from randomized, controlled
trials with important limitations (eg, inconsistent results,
methodologic flaws, imprecise results, extrapolation from a different
population or setting) or very strong evidence of some other form.
Further research (if performed) is likely to have an impact on our
confidence in the estimates of benefit and risk, and may change the