|A Grade 1C recommendation is a strong
recommendation; however, some of the key evidence supporting the
recommendation is of low quality. While we currently believe the
recommendation applies to most patients, the recommendation may change
when higher quality evidence becomes available.
|A Grade 1 recommendation is a strong
recommendation. It means that we believe that if you follow the
recommendation, you will be doing more good than harm for most, if not
all of your patients.
|Grade C means the evidence comes from
observational studies, unsystematic clinical experience, or from
randomized, controlled trials with serious flaws. Any estimate of
effect is uncertain.