|A Grade 1B recommendation is a strong
recommendation, and applies to most patients. Clinicians should follow
a strong recommendation unless a clear and compelling rationale for an
alternative approach is present.
|A Grade 1 recommendation is a strong
recommendation. It means that we believe that if you follow the
recommendation, you will be doing more good than harm for most, if not
all of your patients.
|Grade B means that the best estimates
of the critical benefits and risks come from randomized, controlled
trials with important limitations (eg, inconsistent results,
methodologic flaws, imprecise results, extrapolation from a different
population or setting) or very strong evidence of some other form.
Further research (if performed) is likely to have an impact on our
confidence in the estimates of benefit and risk, and may change the