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Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction

INTRODUCTION

The metabolism of bilirubin by the liver is comprised of four distinct but interrelated stages (see "Bilirubin metabolism"):

Uptake from the circulation

Intracellular storage

Conjugation with glucuronic acid

Biliary excretion

                     

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Literature review current through: Aug 2014. | This topic last updated: Feb 12, 2014.
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