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Medline ® Abstract for Reference 95

of 'Fluoropyrimidine-associated cardiotoxicity: Incidence, clinical manifestations, mechanisms, and management'

Provocative testing for coronary reactivity and spasm.
Zaya M, Mehta PK, Merz CN
J Am Coll Cardiol. 2014 Jan;63(2):103-9. Epub 2013 Nov 6.
Coronary spasm is an important and often overlooked etiology of chest pain. Although coronary spasm, or Prinzmetal's angina, has been thought of as benign, contemporary studies have shown serious associated adverse outcomes, including acute coronary syndrome, arrhythmia, and death. Definitive diagnosis of coronary spasm can at times be difficult, given the transience of symptoms. Numerous agents have been historically described for provocative testing. We provide a review of published data for the role of provocation testing in the diagnosis of coronary spasm.
Barbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, California.