Successful Completion of Adjuvant Chemotherapy in a Patient With Colon Cancer Experiencing 5-Fluorouracil-Induced Cardiac Vasospasm

Clin Colorectal Cancer. 2016 Jun;15(2):e61-3. doi: 10.1016/j.clcc.2015.10.004. Epub 2015 Nov 10.

Authors

Craig A Vargo¹, Marlo Blazer², Joshua Reardon², Martha Gulati³, Tanios Bekaii-Saab⁴

Affiliations

¹ Department of Pharmacy, The James Cancer Hospital and Solove Research Institute at The Ohio State University, Columbus, OH. Electronic address: Craig.Vargo@osumc.edu.
² Department of Pharmacy, The James Cancer Hospital and Solove Research Institute at The Ohio State University, Columbus, OH.
³ Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
⁴ Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

PMID: 26701613
DOI: 10.1016/j.clcc.2015.10.004

No abstract available

Keywords: 5-Fluorouracil; Cardiotoxicity; Colon cancer; Fluoropyrimidines; Vasospastic angina.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / drug therapy*
Antineoplastic Agents / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Cardiotoxicity / drug therapy
Cardiotoxicity / etiology
Chemotherapy, Adjuvant
Colonic Neoplasms / drug therapy*
Coronary Vasospasm / chemically induced*
Coronary Vasospasm / drug therapy
Diltiazem / therapeutic use
Female
Fluorouracil / administration & dosage
Fluorouracil / adverse effects*
Humans
Leucovorin / administration & dosage
Leucovorin / adverse effects
Middle Aged
Nifedipine / therapeutic use
Organoplatinum Compounds / administration & dosage
Organoplatinum Compounds / adverse effects
Vasodilator Agents / therapeutic use

Substances

Antineoplastic Agents
Organoplatinum Compounds
Vasodilator Agents
Diltiazem
Nifedipine
Leucovorin
Fluorouracil

Supplementary concepts

Folfox protocol