Fever is an abnormal elevation of body temperature that occurs as part of a specific biologic response that is mediated and controlled by the central nervous system.
The pathophysiology and treatment of fever in infants and children will be reviewed here. Other causes of elevated body temperature in children and the evaluation and management of fever in specific populations of infants and children are discussed separately:
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Ward MA. Fever: Pathogenesis and treatment. In: Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, 7th, Cherry JD, Harrison GJ, Kaplan SL, et al. (Eds), Elsevier Saunders, Philadelphia 2014. p.83.
Health supervision: First week visit. In: Bright Futures Guidelines for Health Supervision, 3rd ed, Hagan JF, Shaw JS, Duncan PM. (Eds), American Academy of Pediatrics, Elk Grove Village, IL 2008. p.289.
National Institute for Health and Care Excellence. Feverish illness in children (CG160). May 2013. http://guidance.nice.org.uk/CG160 (Accessed on June 14, 2013).
U.S. Food and Drug Administration. Acetaminophen: Drug safety communication - association with risk of serious skin reactions. http://www.fda.gov/Drugs/DrugSafety/ucm363041.htm (Accessed on September 04, 2013).