Evaluation of the menstrual cycle and timing of ovulation
- Corrine K Welt, MD
Corrine K Welt, MD
- Professor of Medicine
- University of Utah School of Medicine
- Section Editors
- Robert L Barbieri, MD
Robert L Barbieri, MD
- Editor-in-Chief — Obstetrics, Gynecology and Women's Health
- Section Editor — General Gynecology and Female Reproductive Endocrinology
- Kate Macy Ladd Professor of Obstetrics, Gynecology and Reproductive Biology
- Harvard Medical School
- William F Crowley, Jr, MD
William F Crowley, Jr, MD
- Section Editor — Female Reproductive Endocrinology
- Daniel K. Podolsky Professor of Medicine
- Harvard Medical School
There are a number of settings in which evaluation of the menstrual cycle may be important. A common question is whether a particular woman ovulates, an issue that can arise in a number of different settings.
●Some women have irregular cycles (oligomenorrhea) and wish to determine how abnormal they are.
●Other women have heavy and painful menstrual periods (hypermenorrhea and dysmenorrhea) that may be associated with anovulatory cycles.
●Some women with apparently normal cycles fail to conceive and wish to know both whether they ovulate and, if so, how to optimize the timing of intercourse.
The detection and timing of ovulation will be reviewed here. The sequence of events occurring in the normal menstrual cycle, with a detailed description of the different phases, is discussed separately (see "Physiology of the normal menstrual cycle"). A discussion of female infertility is found elsewhere. (See "Overview of infertility".)
- Filicori M, Butler JP, Crowley WF Jr. Neuroendocrine regulation of the corpus luteum in the human. Evidence for pulsatile progesterone secretion. J Clin Invest 1984; 73:1638.
- Stanford JB, White GL, Hatasaka H. Timing intercourse to achieve pregnancy: current evidence. Obstet Gynecol 2002; 100:1333.
- McGovern PG, Myers ER, Silva S, et al. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril 2004; 82:1273.
- Taylor AE, Khoury RH, Crowley WF Jr. A comparison of 13 different immunometric assay kits for gonadotropins: implications for clinical investigation. J Clin Endocrinol Metab 1994; 79:240.
- Sherman BM, West JH, Korenman SG. The menopausal transition: analysis of LH, FSH, estradiol, and progesterone concentrations during menstrual cycles of older women. J Clin Endocrinol Metab 1976; 42:629.