Medline ® Abstracts for References 68-70
of 'Evaluation of suspected obstructive sleep apnea in children'
Polysomnographic and clinical findings in children with obstructive sleep apnea.
Leach J, Olson J, Hermann J, Manning S
Arch Otolaryngol Head Neck Surg. 1992;118(7):741.
A retrospective study was conducted to determine which types of children might have polysomnographic findings that are most compatible with obstructive sleep apnea (OSA). The charts of 93 patients who were aged 18 months to 12 years were examined. All 93 patients had symptoms that were initially suggestive of OSA, and they underwent polysomnography. The types of presenting symptoms and associated illnesses were noted. Physical findings, including height, weight, and tonsil size, were examined. Of 93 patients with symptoms that were suggestive of OSA, 34 met sleep study criteria for OSA. In 44 patients, OSA was not demonstrated, and 15 patients had other results. On the basis of age, sex, and symptoms, no significant differences could be found between the group with OSA and the group with normal polysomnographic findings. Cor pulmonale, tonsil hypertrophy, and failure to thrive were associated with OSA. Surprisingly, obesity was not significantly associated with OSA.
Department of Otolaryngology, University of Texas Southwestern Medical School, Dallas 75235.
Sleep-disordered breathing in children.
Am J Respir Crit Care Med. 2001;164(1):16.
The Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA. firstname.lastname@example.org
High prevalence of allergic sensitization in children with habitual snoring and obstructive sleep apnea.
McColley SA, Carroll JL, Curtis S, Loughlin GM, Sampson HA
STUDY OBJECTIVE: To determine whether allergic sensitization occurs frequently in children with habitual snoring and whether allergy predicts the occurrence of obstructive sleep apnea syndrome (OSAS) in snoring children.
DESIGN: Prospective study of 39 children with habitual snoring who were referred for polysomnography.
SETTING: Pediatric pulmonary sleep disorders clinic in a tertiary referral center.
MEASUREMENTS: Subjects underwent a complete history and physical examination. To assess for the presence of allergic sensitization, a multiantigen radioallergosorbent test (RAST) was performed on serum samples. Subjects then underwent nocturnal polysomnography to determine the presence and severity of OSAS.
RESULTS: Fourteen subjects (36%) demonstrated sensitivity to allergens; this is higher than expected for the general pediatric population. The frequency of OSAS was increased in subjects with positive RAST results compared to those with negative RAST results (57% vs 40%; chi 2 = 9.11; p<0.01).
CONCLUSION: Allergy is frequently present in pediatric patients with habitual snoring. Furthermore, the presence of allergy is associated with an increased risk of OSAS in this population.
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, USA.