Epidemiology, etiology, and diagnosis of nasopharyngeal carcinoma
- Edwin P Hui, MD
Edwin P Hui, MD
- Clinical Associate Professor (Honorary)
- Department of Clinical Oncology
- Prince of Wales Hospital
- The Chinese University of Hong Kong
- Anthony TC Chan, MD
Anthony TC Chan, MD
- Professor of Clinical Oncology
- Prince of Wales Hospital
- The Chinese University of Hong Kong
- Section Editors
- Bruce E Brockstein, MD
Bruce E Brockstein, MD
- Section Editor — Cancer of the Head and Neck
- Clinical Professor of Medicine
- University of Chicago Pritzker School of Medicine
- David M Brizel, MD
David M Brizel, MD
- Section Editor — Radiation Therapy
- Leonard R Prosnitz Professor of Radiation Oncology
- Professor of Otolaryngology Head & Neck Surgery
- Duke University Cancer Institute
- Marvin P Fried, MD, FACS
Marvin P Fried, MD, FACS
- Section Editor — Head and Neck Surgery
- Professor and University Chairman, Department of Otorhinolaryngology - Head and Neck Surgery
- Montefiore Medical Center, Albert Einstein College of Medicine
Nasopharyngeal carcinoma is the predominant tumor type arising in the nasopharynx, the narrow tubular passage behind the nasal cavity. It differs from other head and neck squamous cell carcinomas in epidemiology, histology, natural history, and response to treatment.
This topic discusses the epidemiology, etiology, diagnosis, and staging of nasopharyngeal carcinoma. The pathology and treatment of nasopharyngeal carcinoma are presented elsewhere.
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- Geographic and ethnic distribution
- Sex and age distribution
- Secular trend
- ETIOLOGY AND RISK FACTORS
- Epstein-Barr virus
- Human papillomavirus
- Molecular pathogenesis
- CLINICAL PRESENTATION
- INITIAL DIAGNOSTIC EVALUATION
- SCREENING BASED ON EBV VIRUS TESTING
- Monitoring for treatment response and recurrence
- SUMMARY AND RECOMMENDATIONS