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Epidemiology, clinical manifestations, and diagnosis of genital herpes simplex virus infection

Mary A Albrecht, MD
Section Editor
Martin S Hirsch, MD
Deputy Editor
Jennifer Mitty, MD, MPH


Genital herpes simplex virus (HSV) infections are a major global public health problem:

A dramatic upsurge in genital HSV infections has been documented from seroprevalence studies.

There is a wide diversity of the clinical spectrum of genital HSV disease.

Like all herpes virus strains, HSV establishes a latent state followed by viral reactivation and recurrent local disease.

Perinatal transmission of HSV can lead to significant fetal morbidity and mortality.


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Literature review current through: Sep 2016. | This topic last updated: Feb 29, 2016.
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