Medline ® Abstract for Reference 63
of 'Epidemiology and pathogenesis of Legionella infection'
[Legionella pneumonia in patients treated with infliximab].
Vinter H, Nielsen HI
Ugeskr Laeger. 2009;171(4):247.
Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease and psoriasis, respectively. We conclude that legionella infections are probably more frequent in patients receiving immunosuppressive therapy with tumour necrosis factor-alfa inhibitors than in the background population.
Infektionsmedicinsk Afdeling, Aalborg Sygehus Syd, DK-9000 Aalborg.