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Medline ® Abstract for Reference 54

of 'Drug-induced thrombotic microangiopathy'

54
TI
Quinine-induced disseminated intravascular coagulation.
AU
Spearing RL, Hickton CM, Sizeland P, Hannah A, Bailey RR
SO
Lancet. 1990;336(8730):1535.
 
Recurrent disseminated intravascular coagulation occurred in 3 women after ingestion of quinine tablets for cramp. All had circulating quinine-dependent antibodies to platelets and in 2 there was initial evidence of antibody consumption, with low titres that rose steeply over the next few days and remained high for many months.
AD
Department of Haematology, Christchurch Hospital, New Zealand.
PMID