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Medline ® Abstract for Reference 84

of 'Drug-induced immune thrombocytopenia'

84
TI
Gold induced thrombocytopenia: 12 cases and a review of the literature.
AU
Adachi JD, Bensen WG, Kassam Y, Powers PJ, Bianchi FA, Cividino A, Kean WF, Rooney PJ, Craig GL, Buchanan WW
SO
Semin Arthritis Rheum. 1987;16(4):287.
 
Gold induced thrombocytopenia is immune mediated, with the production of platelet associated IgG leading to peripheral platelet destruction. An association with HLA-DR3 has been demonstrated. Corticosteroid therapy is effective in treatment, although other modes of therapy may be as efficacious.
AD
PMID