Irinogenetics: what is the right star?

J Clin Oncol. 2006 May 20;24(15):2221-4. doi: 10.1200/JCO.2005.05.2464. Epub 2006 Apr 24.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Alleles
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Asian People
  • Camptothecin / analogs & derivatives*
  • Camptothecin / metabolism
  • Camptothecin / pharmacology
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / genetics
  • DNA Topoisomerases, Type I / genetics
  • Drug-Related Side Effects and Adverse Reactions / genetics
  • Drug-Related Side Effects and Adverse Reactions / metabolism
  • Glucuronosyltransferase / genetics*
  • Humans
  • Irinotecan
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics
  • Neoplasms / drug therapy
  • Neoplasms / genetics*
  • Pharmacogenetics*
  • Polymorphism, Genetic
  • Topoisomerase I Inhibitors

Substances

  • Antineoplastic Agents, Phytogenic
  • Topoisomerase I Inhibitors
  • Irinotecan
  • UGT1A1 enzyme
  • Glucuronosyltransferase
  • DNA Topoisomerases, Type I
  • Camptothecin