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Donor selection for hematopoietic cell transplantation

Robert S Negrin, MD
Section Editor
Nelson J Chao, MD
Deputy Editor
Alan G Rosmarin, MD


The selection of a donor is a critical element contributing to the success of hematopoietic cell transplantation (HCT). There are several possible donor options:

An identical twin (syngeneic, HLA identical)

A sibling, relative, or unrelated donor (allogeneic, which can be HLA identical, haploidentical, or mismatched)

Umbilical cord blood (allogeneic, which can be HLA identical, haploidentical, or mismatched)

The patient (autologous, HLA identical)


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Literature review current through: Sep 2016. | This topic last updated: Sep 9, 2016.
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