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Diagnostic approach to the patient with newly identified chronic kidney disease

Pedram Fatehi, MD, MPH
Chi-yuan Hsu, MD, MSc
Section Editor
Gary C Curhan, MD, ScD
Deputy Editor
Alice M Sheridan, MD


Patients with kidney disease may have a variety of clinical presentations. Some have symptoms or signs that are directly referable to the kidney (such as hematuria) or to associated extrarenal manifestations (edema, hypertension, signs of uremia). Many patients are asymptomatic and are incidentally noted to have an elevated serum creatinine, which may have been (or upon further investigation is found to be) stable for years.

This topic reviews the evaluation of patients with newly identified chronic kidney disease (CKD).

The evaluation of patients who present with subacute or acute kidney injury (AKI) is discussed elsewhere. (See "Diagnostic approach to adult patients with subacute kidney injury in an outpatient setting" and "Evaluation of acute kidney injury among hospitalized adult patients".)

The management of CKD patients is discussed elsewhere. (See "Evaluation of acute kidney injury among hospitalized adult patients" and "Overview of the management of chronic kidney disease in adults".)


The evaluation of patients with an elevated creatinine of any duration includes:

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Literature review current through: Nov 2017. | This topic last updated: Oct 26, 2017.
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