Medline ® Abstract for Reference 52
of 'Diagnosis of primary aldosteronism'
52
TI
Primary hyperaldosteronism: effect of adrenal vein sampling on surgical outcome.
AU
Nwariaku FE, Miller BS, Auchus R, Holt S, Watumull L, Dolmatch B, Nesbitt S, Vongpatanasin W, Victor R, Wians F, Livingston E, Snyder WH 3rd
SO
Arch Surg. 2006;141(5):497.
HYPOTHESIS:
Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism.
DESIGN:
Retrospective review.
SETTING:
University medical center.
PATIENTS:
Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism.
MAIN OUTCOME MEASURES:
We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes.
RESULTS:
Mean +/- SEM adrenal nodule size was 1.54 +/- 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it wassuccessful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia.
CONCLUSION:
Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.
AD
Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75390-9156, USA. fiemu.nwariaku@utsouthwestern.edu
PMID