Diagnosis of intravascular catheter-related infections
- Jeffrey D Band, MD
Jeffrey D Band, MD
- Health System Chair, Healthcare Epidemiology and International Medicine
- Beaumont Health System
- Former Director of Infectious Diseases (1985-2013)
- Beaumont Hospital-Royal Oak
- Royal Oak, MI
- Professor of Medicine
- Oakland University William Beaumont School of Medicine
- Section Editors
- Anthony Harris, MD, MPH
Anthony Harris, MD, MPH
- Section Editor — Hospital Acquired Infections
- Professor of Medicine
- University of Maryland School of Medicine
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
Approximately 80,000 central venous catheter-related bloodstream infections occur in United States intensive care units each year [1,2]. In general, the diagnostic approach to catheter-related blood stream infection (CRBSI) consists of clinical evaluation and microbiologic confirmation with blood and catheter cultures.
The clinical features and diagnosis of CRBSI will be reviewed here. Issues related to treatment of CRBSI are discussed in detail separately. (See "Treatment of intravascular catheter-related infections".)
For surveillance purposes, the Centers for Disease Control has introduced the term laboratory-confirmed bloodstream infection (LCBI) . LCBI must meet at least one of the following criteria:
●Patient has a recognized pathogen cultured from one or more blood cultures and the pathogen is not related to an infection at another site.
●Patient has fever, chills, and/or hypotension as well as positive laboratory cultures from two or more blood samples drawn on separate occasions which are not related to infection at another site and do not reflect contamination.
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