Diagnosis of intravascular catheter-related infections
- Jeffrey D Band, MD
Jeffrey D Band, MD
- Health System Chair, Healthcare Epidemiology and International Medicine
- Beaumont Health System
- Former Director of Infectious Diseases (1985-2013)
- Beaumont Hospital-Royal Oak
- Royal Oak, MI
- Professor of Medicine
- Oakland University William Beaumont School of Medicine
- Rochester, MI
- Section Editors
- Anthony Harris, MD, MPH
Anthony Harris, MD, MPH
- Section Editor — Hospital Acquired Infections
- Professor of Medicine
- University of Maryland School of Medicine
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
Approximately 80,000 central venous catheter–related bloodstream infections occur in United States intensive care units each year [1,2]. In general, the diagnostic approach to catheter-related bloodstream infection (CRBSI) consists of clinical evaluation and microbiologic confirmation with separate blood cultures obtained from the catheter as well as a peripheral vein.
The clinical features and diagnosis of CRBSI will be reviewed here. Issues related to treatment of CRBSI are discussed in detail separately. (See "Treatment of intravascular catheter-related infections".)
For surveillance purposes, the Centers for Disease Control and Prevention (CDC) has introduced the term laboratory-confirmed bloodstream infection (LCBI) . LCBI must meet at least one of the following criteria:
●Patient has a recognized pathogen cultured from one or more blood cultures, and the pathogen is not related to an infection at another site.
●Patient has at least one of the following signs or symptoms: fever (>38.0°C), chills, or hypotension, and the pathogen is not related to an infection at another site or, if the organism is a common commensal, it must be present from two or more blood cultures drawn on separate occasions.
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