Medline ® Abstract for Reference 15
of 'Cutaneous side effects of conventional chemotherapy agents'
Melanonychia induced by topical 5-fluorouracil.
Baran R, Laugier P
Br J Dermatol. 1985;112(5):621.
Melanonychia was induced by the topical application of 5-fluorouracil in the treatment of periungual warts affecting two fingers. The pigmentation, involving the lunula of the nails of all fingers, was identical to that induced by systemically administered cytotoxic drugs.