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Medline ® Abstract for Reference 6

of 'Cutaneous manifestations of internal malignancy'

6
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Malignant Acanthosis Nigricans Associated with Ovarian Cancer.
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Oh CW, Yoon J, Kim CY
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Case Rep Dermatol. 2010;2(2):103. Epub 2010 Jul 2.
 
Malignant acanthosis nigricans is a cutaneous eruption characterized by symmetric hyperpigmented hyperkeratosis, dermal papillomatosis, and mucosal involvement associated with internal malignancies. Tripe palms refers to a characteristic velvety thickening of the palms, with exaggeration of normal skin markings. We present the second case of ovarian cancer in association with two coexisting paraneoplastic dermatoses occurring in a 57-year-old Korean female. The presence of acanthosis nigricans in conjunction with tripe palms in a female patient is highly suggestive of an internal malignancy including an ovarian cancer and demands an extensive search for the hidden ovarian cancer.
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Department of Dermatology, School of Medicine, Kangwon National University Hospital, Hyoja-dong, Chuncheon, Korea.
PMID