Medline ® Abstract for Reference 24
of 'Cutaneous manifestations of internal malignancy'
Acquired ichthyosis as a paraneoplastic syndrome in Hodgkin's disease.
Riesco Martínez MC, Muñoz Martín AJ, Zamberk Majlis P, Adeva Alfonso J, Sabin Domínguez P, García Alfonso P, Pérez Fernández R
Clin Transl Oncol. 2009;11(8):552.
An 80-year-old man was admitted to hospital with low-grade fever, weight loss, asthenia and anorexia. Physical examination revealed generalised ichthyosis with palmoplantar hyperkeratosis. CT scan showed retroperitoneal and inguinal lymph node enlargement. An inguinal lymph node biopsy revealed Hodgkin's disease (nodular-sclerosing subtype). The patient received chemotherapy, showing a clear improvement of both skin lesions and lymph nodes.
Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón Madrid, Spain.