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Medline ® Abstract for Reference 10

of 'Cutaneous manifestations of internal malignancy'

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Malignant acanthosis nigricans: a review.
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Rigel DS, Jacobs MI
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J Dermatol Surg Oncol. 1980;6(11):923.
 
Malignant acanthosis nigricans is a dermatosis that appears grossly as a hyperpigmented, velvety, or verrucous hyperplasia of the epidermis, most marked in flexural areas. It is always associated with a malignancy. In 277 cases reviewed, the condition was associated with gastric carcinomas in 55.5%, with other intra-abdominal carcinomas in 17.7%, and with malignancies in other sites in 26.8%. Current theories for the association and pathogenesis of the cutaneous process are discussed.
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PMID