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Medline ® Abstract for Reference 61

of 'Critical illness during pregnancy and the peripartum period'

Magnetic resonance imaging in Posterior Reversible Encephalopathy Syndrome: report of three cases and review of literature.
Finocchi V, Bozzao A, Bonamini M, Ferrante M, Romano A, Colonnese C, Fantozzi LM
Arch Gynecol Obstet. 2005;271(1):79. Epub 2004 Oct 9.
INTRODUCTION: Eclampsia is one of the main causes of Posterior Reversible Encephalopathy Syndrome (PRES) a recent clinico-neuroradiological entity represented by characteristic MR findings of a symmetric bilateral subcortical/cortical hyperintensity in T2-weighted images, more often in parieto-occipital lobes, accompanied by clinical neurological alterations. Neuroradiological and clinical alterations are commonly completely reversible although ischemic evolution has been described. The pathophysiology is still a matter of debate. Specific magnetic resonance (MR) techniques, such as FLAIR (fluid attenuated inversion recovery) and DWI (diffusion weighted images) sequences, have improved the ability to detect subcortical/cortical lesions and helped to clarify the underlying pathophysiological mechanism of cerebrovascular involvement, which results important for an appropriate therapeutic decision.
CASE REPORT AND DISCUSSION: We report the MR imaging findings of three patients with eclampsia and PRES as well as a careful review of literature.
Department of Neuroradiology, University of Rome La Sapienza, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy. vaninafinocchi@libero.it