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Medline ® Abstract for Reference 60

of 'Critical illness during pregnancy and the peripartum period'

Posterior reversible encephalopathy syndrome, part 1: fundamental imaging and clinical features.
Bartynski WS
AJNR Am J Neuroradiol. 2008 Jun;29(6):1036-42. Epub 2008 Mar 20.
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state coupled with a unique CT or MR imaging appearance. Recognized in the setting of a number of complex conditions (preeclampsia/eclampsia, allogeneic bone marrow transplantation, organ transplantation, autoimmune disease and high dose chemotherapy) the imaging, clinical and laboratory features of this toxic state are becoming better elucidated. This review summarizes the basic and advanced imaging features of PRES, along with pertinent features of the clinical and laboratory presentation and available histopathology. Many common imaging/clinical/laboratory observations are present among these patients, despite the perception of widely different associated clinical conditions.
Department of Radiology, Division of Neuroradiology, University of Pittsburgh, Presbyterian University Hospital, Pittsburgh, PA 15213, USA. bartynskiws@upmc.edu