Cogan’s syndrome (CS) is a chronic inflammatory disorder that most commonly affects young adults. Clinical hallmarks are interstitial keratitis (IK) and vestibuloauditory dysfunction . Associations between CS and systemic vasculitis, as well as aortitis, also exist [2-4].
The pathology, pathogenesis, clinical manifestations, and treatment of CS will be presented here.
Limited autopsy data derived from temporal bone specimens of patients with Cogan’s syndrome (CS) reveal a range of findings, including [5-7]:
●Lymphocyte and plasma cell infiltration of the spiral ligament