Medline ® Abstract for Reference 56
of 'Clostridium difficile infection in adults: Clinical manifestations and diagnosis'
Nonutility of repeat laboratory testing for detection of Clostridium difficile by use of PCR or enzyme immunoassay.
Aichinger E, Schleck CD, Harmsen WS, Nyre LM, Patel R
J Clin Microbiol. 2008;46(11):3795. Epub 2008 Sep 10.
The diagnostic gains of repeat testing for Clostridium difficile by enzyme immunoassay and PCR (i.e., initial negative result followed by positive result) within a 7-day period were 1.9 and 1.7%, respectively. There is little value of repeat testing for C. difficile by enzyme immunoassay or PCR.
Division of Clinical Microbiology, College of Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.