Medline ® Abstract for Reference 35
of 'Clostridium difficile infection in adults: Clinical manifestations and diagnosis'
Clostridium difficile-associated disease: new challenges from an established pathogen.
Sunenshine RH, McDonald LC
Cleve Clin J Med. 2006;73(2):187.
Clostridium difficile-associated disease (CDAD) can range from uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing, possibly due to a new strain. Transmission of C difficile occurs primarily in health care facilities via the fecal-oral route following transient contamination of the hands of health care workers and patients; contamination of the patient care environment also plays an important role.
Division of Healthcare Quality Promotion, US Centers for Disease Control and Prevention, USA.