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Medline ® Abstract for Reference 21

of 'Clostridium difficile infection in adults: Clinical manifestations and diagnosis'

Relapse versus reinfection: surveillance of Clostridium difficile infection.
Kamboj M, Khosa P, Kaltsas A, Babady NE, Son C, Sepkowitz KA
Clin Infect Dis. 2011 Nov;53(10):1003-6. Epub 2011 Oct 5.
Molecular typing was used to examine surveillance definitions for recurrent Clostridium difficile-associated diarrhea. Among 102 patients, 85 had a second episode within 8 weeks, 88% of which were relapses. Of 49 second episodes occurring after>8 weeks, 65% were relapses. Categorization of a recurrent episode occurring after>8 weeks as a new infection may misrepresent the majority of episodes for surveillance.
Infectious Disease Service, Infection Control, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. kambojm@mskcc.org