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Medline ® Abstract for Reference 98

of 'Clostridium difficile in adults: Treatment'

98
TI
Gamma globulin administration in relapsing Clostridium difficile-induced pseudomembranous colitis with a defective antibody response to toxin A.
AU
Warny M, Denie C, Delmée M, Lefebvre C
SO
Acta Clin Belg. 1995;50(1):36.
 
A 53-year-old woman suffered six episodes of Clostridium difficile-pseudomembranous colitis. The serological follow-up demonstrated the absence of a rise in IgG and IgA to toxin A. Human pooled gamma globulin was administered during the fifth relapse and raised IgG levels to toxin A. Normal stools reappeared a week later. The role of the antibodies to toxin A and gamma globulin in C. difficile colitis are discussed.
AD
Département de Microbiologie, UniversitéCatholique de Louvain, Bruxelles, Belgique.
PMID