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Medline ® Abstract for Reference 82

of 'Clostridium difficile in adults: Treatment'

82
TI
In vitro activities of OPT-80 and comparator drugs against intestinal bacteria.
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Finegold SM, Molitoris D, Vaisanen ML, Song Y, Liu C, Bolaños M
SO
Antimicrob Agents Chemother. 2004;48(12):4898.
 
The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization resistance.
AD
Medical Service, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA. sidfinegol@aol.com
PMID