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Medline ® Abstract for Reference 81

of 'Clostridium difficile in adults: Treatment'

81
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Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection.
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Herpers BL, Vlaminckx B, Burkhardt O, Blom H, Biemond-Moeniralam HS, Hornef M, Welte T, Kuijper EJ
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Clin Infect Dis. 2009;48(12):1732.
 
Clostridium difficile infection (CDI) has become more refractory to standard therapy. We describe 4 patients with severe refractory CDI who were successfully treated with tigecycline. Symptoms improved within 1 week. No relapses were observed. This favorable outcome suggests that tigecycline might be a useful alternative for treating severe refractory CDI.
AD
Department of Medical Microbiology and Immunology, St. Antonius Hospital, PO Box 2500, Nieuwegein 3430 EM, The Netherlands. b.herpers@antonius.net
PMID