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Medline ® Abstract for Reference 52

of 'Clostridium difficile in adults: Treatment'

52
TI
Vancomycin Taper and Pulse Regimen With Careful Follow-up for Patients With Recurrent Clostridium difficile Infection.
AU
Sirbu BD, Soriano MM, Manzo C, Lum J, Gerding DN, Johnson S
SO
Clin Infect Dis. 2017;65(8):1396.
 
We retrospectively studied vancomycin taper and pulse treatment on 100 consecutive, evaluable patients with recurrent Clostridium difficile infection. Following taper to once-daily vancomycin dosing, 22 of 36 patients (61%) who received every-other-day dosing (QOD) and 50 of 64 (81%) who received QOD followed by every-third-day dosing were cured (P = .03).
AD
Loyola University Medical Center, Maywood.
PMID