Medline ® Abstract for Reference 52
of 'Clostridium difficile in adults: Treatment'
Vancomycin Taper and Pulse Regimen With Careful Follow-up for Patients With Recurrent Clostridium difficile Infection.
Sirbu BD, Soriano MM, Manzo C, Lum J, Gerding DN, Johnson S
Clin Infect Dis. 2017;65(8):1396.
We retrospectively studied vancomycin taper and pulse treatment on 100 consecutive, evaluable patients with recurrent Clostridium difficile infection. Following taper to once-daily vancomycin dosing, 22 of 36 patients (61%) who received every-other-day dosing (QOD) and 50 of 64 (81%) who received QOD followed by every-third-day dosing were cured (P = .03).
Loyola University Medical Center, Maywood.