Clinical syndromes of stunned or hibernating myocardium
- David M Shavelle, MD
David M Shavelle, MD
- Associate Clinical Professor
- University of Southern California
- Section Editors
- Bernard J Gersh, MB, ChB, DPhil, FRCP, MACC
Bernard J Gersh, MB, ChB, DPhil, FRCP, MACC
- Editor-in-Chief — Cardiovascular Medicine
- Section Editor — Coronary Heart Disease; Myopericardial Disease
- Professor of Medicine
- Mayo Clinic College of Medicine
- Jeroen J Bax, MD, PhD
Jeroen J Bax, MD, PhD
- Section Editor — Noninvasive Cardiac Imaging and Stress Testing
- Professor of Cardiology
- Leiden University Medical Center, The Netherlands
Left ventricular (LV) dysfunction, which may be an important consequence of coronary artery disease, can result from acute myocardial ischemia or myocardial infarction [1,2]. In addition, two other clinical syndromes can be associated with LV dysfunction:
●Transient postischemic dysfunction, called "stunned" myocardium
●Chronic, but potentially reversible, ischemic dysfunction, called "hibernating" myocardium
In patients with the latter disorder, LV function may improve markedly and mortality may be reduced following successful coronary revascularization. The time course of recovery is variable.
The clinical syndromes associated with stunned and hibernating myocardium and the methods used to detect stunned myocardium will be reviewed here. The pathophysiology of these disorders and the diagnosis and treatment of hibernating myocardium are discussed separately. (See "Pathophysiology of stunned or hibernating myocardium" and "Evaluation of hibernating myocardium" and "Ischemic cardiomyopathy: Treatment and prognosis".)
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