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Clinical pathological cases in gastroenterology: Stomach

Andres Gelrud, MD, MMSc
Section Editor
J Thomas Lamont, MD
Deputy Editor
Shilpa Grover, MD, MPH, AGAF


The following cases are meant to illustrate clinical, pathological, and endoscopic findings in patients with a variety of gastric conditions. Detailed discussions on the specific disorders are presented on corresponding topic reviews.


A 70 year old man underwent an upper endoscopy for the evaluation of a two day history of melena and new onset dizziness. The patient's only medical problem is rheumatoid arthritis treated with ibuprofen over the past three years. His weight has been stable and he denies having fevers, nausea, vomiting, abdominal pain, or hematochezia. An upper endoscopy revealed the following (picture 1 and picture 2). (See "Clinical characteristics of well-differentiated neuroendocrine (carcinoid) tumors arising in the tubular digestive tract, lung, and genitourinary tract".)


A 45 year old man with no significant past medical history underwent an upper endoscopy and colonoscopy for the evaluation of iron deficiency anemia and nonspecific abdominal pain. The endoscopy revealed a single 2 cm by 3 cm ulcerated lesion of malignant appearance in the stomach body (picture 3 and picture 4). The colonoscopy was normal to the terminal ileum. (See "Epidemiology, clinical manifestations, pathologic features, and diagnosis of diffuse large B cell lymphoma".)


A 52 year old woman underwent an upper endoscopy for the evaluation of persistent acid reflux and epigastric abdominal discomfort. The patient's only medical condition is gastroesophageal reflux disease for which she takes a proton pump inhibitor. Endoscopy revealed a small polyp in the gastric fundus (picture 5 and picture 6). (See "Gastric polyps".)


A 56 year old male underwent an upper endoscopy for the evaluation of worsening heartburn and nausea. Upper endoscopy revealed two small 4 mm yellow nodules in the fundus (picture 7 and picture 8); the esophagus and duodenum were normal.

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Literature review current through: Dec 2017. | This topic last updated: Feb 23, 2017.
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