Medline ® Abstract for Reference 6
of 'Clinical manifestations and treatment of hypokalemia in adults'
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Primary aldosteronism presenting as myoglobinuric acute renal failure.
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Dominic JA, Koch M, Guthrie GP Jr, Galla JH
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Arch Intern Med. 1978;138(9):1433.
Hypokalemia is an uncommon cause of rhabdomyolysis with acute tubular necrosis. We recently treated a patient in whom severe hypokalemia attributed to diuretic therapy antedated acute myoglobinuric renal failure by six months. After recovery, hypokalemia persisted and subsequent evaluation disclosed primary aldosteronism. This case is a unique presentation for primary aldosteronism and illustrates the importance of diagnosis before treatment in hypertension as well as the hazards of hypokalemia.
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