Clinical manifestations and diagnosis of Yersinia infections
- Robert V Tauxe, MD, MPH
Robert V Tauxe, MD, MPH
- Division of Bacterial and Mycotic Diseases
- Centers for Disease Control and Prevention
- Section Editors
- Stephen B Calderwood, MD
Stephen B Calderwood, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine (Microbiology and Immunobiology)
- Harvard Medical School
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
The genus Yersinia includes 11 species, 3 of which are important human pathogens: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis [1,2]. The yersinioses are zoonotic infections of domestic and wild animals; humans are considered incidental hosts that do not contribute to the natural disease cycle.
Y. enterocolitica and Y. pseudotuberculosis cause yersiniosis, a diarrheal illness; human infection with Y. enterocolitica is much more common than human infection with Y. pseudotuberculosis. The clinical manifestations and diagnosis of these infections will be reviewed here. The epidemiology, microbiology, pathogenesis, and treatment of these infections are discussed separately. (See "Epidemiology of yersiniosis" and "Treatment and prevention of Yersinia enterocolitica and Yersinia pseudotuberculosis infection".)
Y. pestis causes plague and is discussed separately. (See "Epidemiology, microbiology and pathogenesis of plague (Yersinia pestis infection)" and "Clinical manifestations, diagnosis, and treatment of plague (Yersinia pestis infection)".)
Major clinical manifestations include acute yersiniosis (eg, acute febrile gastroenteritis) and pseudoappendicitis syndrome. A variety of complications (both gastrointestinal and extraintestinal) and post-infectious sequelae have also been described, as outlined in the following sections .
Acute yersiniosis — The incubation period for yersiniosis is typically 4 to 6 days (range 1 to 14 days) [4-6].To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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