Medline ® Abstract for Reference 179
of 'Clinical manifestations and diagnosis of the myelodysplastic syndromes'
179
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Sideroblastic anaemia with reactive thrombocytosis versus myelodysplastic/myeloproliferative disease.
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Pérez Sánchez I, Pérez Corrala A, Menarguez Palanca J, Mayayo Crespo M, Escudero Soto A, Pintado Cros T
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Leuk Lymphoma. 2003;44(3):557.
The reported incidence of thrombocytosis among cases of refractory anaemia with ring sideroblasts (RARS) may be as high as 15%. We report four additional cases of this association, which appear to be hematologically heterogeneous. One patient clearly represents a case of RARS with reactive thrombocytosis. Two cases have features suggestive of the coincidental occurrence of essential thrombocythemia and RARS. The fourth case could be best classified as a subtype of myelodysplastic/myeloproliferative disease unclassifiable (MDS/MPD U). Only new biological or molecular markers will allow better differentiation between these disorders.
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PMID