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Clinical manifestations and diagnosis of pulmonary sarcoidosis

Talmadge E King, Jr, MD
Section Editor
Kevin R Flaherty, MD, MS
Deputy Editor
Helen Hollingsworth, MD


Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that affects individuals worldwide and is characterized pathologically by the presence of noncaseating granulomas in involved organs. It typically affects young adults, and initially presents with one or more of the following abnormalities:

Bilateral hilar adenopathy

Pulmonary reticular opacities

Skin, joint, and/or eye lesions

An overview of the clinical manifestations and diagnosis of pulmonary sarcoidosis is presented here. Issues relating to extrapulmonary sarcoidosis and the pathogenesis and treatment of sarcoidosis are discussed separately. (See "Pathology and pathogenesis of sarcoidosis" and "Treatment of pulmonary sarcoidosis: Initial therapy with glucocorticoids" and "Treatment of pulmonary sarcoidosis: Disease refractory to glucocorticoid therapy" and "Extrapulmonary manifestations of sarcoidosis".)

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Literature review current through: Nov 2017. | This topic last updated: Jun 19, 2017.
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