Measurement of health-related quality of life in adult patients with birch pollen-associated food allergy

J Dtsch Dermatol Ges. 2016 Apr;14(4):397-404. doi: 10.1111/ddg.12731. Epub 2016 Feb 10.
[Article in English, German]

Abstract

Background: The "Food Allergy Quality of Life Questionnaire - Adult Form" (FAQLQ-AF) is the first freely available questionnaire for the assessment of health-related quality of life (HRQL) in adults with food allergy (FA). We present validation data for the German version as well as data on HRQL in patients with birch pollen-associated FA.

Patients and methods: The Dutch FAQLQ-AF (scale from 1-7, no impairment - maximum impairment) was translated into German. Subsequently, 73 consecutive patients with a history of birch pollen-associated FA (52 women, median age 43 years) were surveyed using questions regarding triggers and symptoms of their FA as well as questions contained in the FAQLQ-AF. Construct validity, internal consistency, and discriminative ability were analyzed.

Results: The foods most frequently reported to elicit allergic reactions included apple (78%), hazelnut (75%), soy drinks (55%), and carrot (52%). Thirty percent of patients exclusively reported symptoms consistent with oral allergy syndrome (OAS). Sixty-four percent reported OAS combined with systemic symptoms, and only 6% were exclusively affected by non-OAS symptoms. The German FAQLQ-AF showed good construct validity (correlation with the food allergy-independent measure: r = 0.81; p < 0.001) and excellent internal consistency (Cronbachs α = 0.98). The mean overall FAQLQ-AF score was 3.7. Women, elderly individuals, and those with multiple relevant food allergies showed a greater impairment of HRQL.

Conclusions: The German FAQLQ-AF questionnaire is a reliable and valid tool for measuring HRQL in patients with birch pollen-associated food allergy.

Publication types

  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Dermatitis, Atopic / diagnosis
  • Dermatitis, Atopic / psychology*
  • Female
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / psychology*
  • Germany / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Psychometrics / methods
  • Psychometrics / standards*
  • Quality of Life / psychology*
  • Reproducibility of Results
  • Rhinitis, Allergic, Seasonal / diagnosis
  • Rhinitis, Allergic, Seasonal / psychology*
  • Self Report / standards
  • Sensitivity and Specificity
  • Surveys and Questionnaires / standards*
  • Translating
  • Young Adult