Clinical manifestations and diagnosis of measles
- Hayley Gans, MD
Hayley Gans, MD
- Associate Professor
- Stanford University Medical Center
- Yvonne A Maldonado, MD
Yvonne A Maldonado, MD
- Professor of Pediatrics and Health Research and Policy
- Stanford University School of Medicine
- Section Editors
- Martin S Hirsch, MD
Martin S Hirsch, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Viral Infections
- Professor of Medicine
- Harvard Medical School
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
Measles is a highly contagious viral illness that occurs worldwide. The infection is characterized by fever, malaise, cough, coryza, and conjunctivitis, followed by exanthem. Following exposure, approximately 90 percent of susceptible individuals will develop measles. The period of contagiousness is estimated to be from five days before the appearance of the rash to four days afterward. The illness may be transmitted in public spaces, even in the absence of person-to-person contact.
Measles virus infection can cause a variety of clinical syndromes, including :
●Classic measles infection in immunocompetent patients
●Modified measles infection in patients with preexisting but incompletely protective anti-measles antibody
●Atypical measles infection in patients immunized with the killed virus vaccine
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- CLINICAL MANIFESTATIONS
- Stages of infection
- Clinical variants
- - Modified measles
- - Atypical measles
- Laboratory findings
- Secondary infection
- - Encephalitis
- - Acute disseminated encephalomyelitis
- - Subacute sclerosing panencephalitis
- Other complications
- GROUPS AT RISK FOR COMPLICATIONS
- Immunocompromised patients
- Pregnant women
- DIFFERENTIAL DIAGNOSIS
- INFORMATION FOR PATIENTS