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Clinical manifestations and diagnosis of central nervous system tumors in children

Authors
Ching Lau, MD, PhD
Wan-Yee Teo, MBBS, FAAP, MRCPCH (UK), PhD
Section Editor
David G Poplack, MD
Deputy Editor
Carrie Armsby, MD, MPH

INTRODUCTION

Central nervous system (CNS) tumors include both nonmalignant and malignant tumors of the brain and spinal cord. Primary malignant CNS tumors are the second most common childhood malignancies, after hematologic malignancies, and are the most common pediatric solid organ tumor [1]. They are the leading cause of death from childhood cancer, surpassing the mortality rate of acute lymphoblastic leukemia [2].

A general overview on the clinical manifestations and diagnosis of CNS tumors in children will be reviewed here. The clinical manifestations and diagnosis of the following specific CNS tumors that occur in children are discussed separately.

Low-grade gliomas (see "Classification and pathologic diagnosis of gliomas")

Malignant gliomas (see "Clinical manifestations and initial surgical approach to patients with high-grade gliomas")

Medulloblastoma (see "Histopathology and molecular pathogenesis of medulloblastoma")

                           

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Literature review current through: Nov 2016. | This topic last updated: Thu Sep 22 00:00:00 GMT+00:00 2016.
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