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Medline ® Abstract for Reference 92

of 'Clinical features, diagnosis, and management of von Hippel-Lindau disease'

Von Hippel-Lindau disease in pregnancy: a brief review.
Hayden MG, Gephart R, Kalanithi P, Chou D
J Clin Neurosci. 2009 May;16(5):611-3. Epub 2009 Mar 3.
The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical intervention should be considered with worsening clinical status. Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma.
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Road, Stanford, California 94305, USA. mghayden@gmail.com