Medline ® Abstract for Reference 104
of 'Clinical features and diagnosis of restless legs syndrome/Willis-Ekbom disease and periodic limb movement disorder in adults'
104
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Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation.
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Driver-Dunckley E, Evidente VG, Adler CH, Hillman R, Hernandez J, Fletcher G, Lyons MK
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Mov Disord. 2006 Aug;21(8):1287-9.
We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.
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Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA.
PMID