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Clinical assessment of the child with suspected cancer

Authors
Kathleen A Neville, MD, MS
C Philip Steuber, MD
Section Editor
Alberto S Pappo, MD
Deputy Editor
Carrie Armsby, MD, MPH

INTRODUCTION

Childhood cancer often is difficult to detect in its early stages because the associated signs and symptoms are nonspecific, insidious in onset, and mimic more common disorders [1]. The time from onset of symptoms to diagnosis of pediatric cancer is variable and ranges from a median time of 21 days for neuroblastoma to 72 days for Ewing Sarcoma [2].

Primary practitioners may have little experience in diagnosing childhood malignancies and may be reluctant to consider the diagnosis because of the ominous implications. Nonetheless, whether or not they express their concern, patients and parents often are worried about childhood cancer, and the possibility of cancer should be discussed when the initial signs and symptoms are suspicious [3].

Optimal treatment of childhood cancer requires a high level of suspicion by the primary care practitioner and early referral to the pediatric oncologist. Early detection and treatment may reduce disease-related morbidity and complications.

The topic will provide an overview of childhood cancer and reviews the evaluation of children and adolescents who present with common signs and symptoms that are suspicious for cancer. The evaluation and treatment of specific malignancies are discussed separately.

OVERVIEW

The following facts about childhood cancer set the stage for a discussion of issues surrounding clinical assessment of the child with suspected cancer:

                        

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Literature review current through: Nov 2016. | This topic last updated: Thu Sep 29 00:00:00 GMT 2016.
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