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Medline ® Abstract for Reference 18

of 'Clinical and laboratory aspects of platelet transfusion therapy'

18
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Platelet transfusion prophylaxis for patients with haematological malignancies: where to now?
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Stanworth SJ, Hyde C, Brunskill S, Murphy MF
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Br J Haematol. 2005;131(5):588.
 
National guidelines for platelet transfusion in many countries recommend that the general platelet transfusion trigger for prophylaxis is 10x10(9)/l. This annotation reviews the evidence for this threshold level and discusses other current unresolved issues relevant to platelet transfusion practice such as the optimal dose and the clinical benefit of a strategy for the prophylactic use of platelet transfusions when the platelet count falls below a given threshold.
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National Blood Service, John Radcliffe Hospital, Headington, Oxford, UK. simon.stanworth@nbs.nhs.uk
PMID