Medline ® Abstract for Reference 113
of 'Classification and evaluation of dystonia'
113
TI
Familial paroxysmal exercise-induced dyskinesia and benign epilepsy: a clinical and neurophysiological study of an uncommon disorder.
AU
Margari L, Perniola T, Illiceto G, Ferrannini E, De Iaco MG, Presicci A, Santostasi R, Ventura P
SO
Neurol Sci. 2000;21(3):165.
We report a family with 6 members affected by a long-lasting paroxysmal exertion-induced dyskinesia. Fasting and stress were precipitating factors. All the patients of this family had also epileptic seizures mainly of generalised type with a favourable outcome. All patients were submitted to a neurophysiological study which included somatosensory evoked potentials by median nerve stimulation (MN-SEPs), somatosensory evoked potentials by posterior tibial nerve stimulation (PTN-SEPs), brainstem auditory evoked potentials (BAEPs), visual evoked potentials (VEPs), motor evoked potentials (MEPs) by magnetic transcranial cortical stimulation (TCS) and electromyography (EMG). The neurophysiological findings suggest a hyperexcitability at the muscular and brain membrane levels, probably due to an ion channel disorder.
AD
Department of Neurological and Psychiatric Sciences, University of Bari, Italy.
PMID