An epidemic of veno-occlusive disease of liver in central India

Lancet. 1976 Aug 7;2(7980):271-2. doi: 10.1016/s0140-6736(76)90727-3.

Abstract

An outbreak of veno-occlusive disease which was probably caused by consumption of cereals mixed with seeds of a plant (Crotalaria sp.) containing pyrrolizidine alkaloids occurred in the Sarguja district of India in November-December 1975. 42% of the 67 recorded cases died.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Disease Outbreaks*
  • Edible Grain / adverse effects
  • Female
  • Food Contamination
  • Humans
  • India
  • Liver / blood supply*
  • Male
  • Middle Aged
  • Plants, Toxic
  • Pyrrolizidine Alkaloids / poisoning*
  • Seeds
  • Thrombophlebitis / chemically induced*

Substances

  • Pyrrolizidine Alkaloids